Substrate: LIM domain kinase 1 (Serine/threonine kinase)
Seq-ID: P53667 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-2833254   MK14_HUMAN
MINT-2833388   MAPK2_HUMAN
MINT-6173989   COF1_HUMAN
MINT-7228333   KAPCA_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding,
heat shock protein binding,
zinc ion binding		 cytoplasm,
growth cone		 protein amino acid phosphorylation,
actin cytoskeleton organization,
positive regulation of actin filament bundle assembly,
Rho protein signal transduction,
negative regulation of ubiquitin-protein ligase activity,
positive regulation of axon extension
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 298 ARQKPVLRSCSIDRSPGAGSL - 17192257
HTP
1.00
 - -
0.53
 - medium
S 302 PVLRSCSIDRSPGAGSLGSPA - 18669648
HTP
1.00
 - -
0.54
 - medium
S 307 CSIDRSPGAGSLGSPASQRKD - 18669648
HTP
0.92
 - -
0.63
 - medium
S 310 DRSPGAGSLGSPASQRKDLGR - 17192257
HTP
0.16
 - -
0.68
 - medium
S 310 DRSPGAGSLGSPASQRKDLGR - 18669648
HTP
0.16
 - -
0.68
 - medium
T 508 LKKPDRKKRYTVVGNPYWMAP MRCKa 11340065
LTP
1.00
 - STYKc
0.29
 - medium
T 508 LKKPDRKKRYTVVGNPYWMAP ROCK_group 10652353
LTP
1.00
 - STYKc
0.29
 - medium
T 508 LKKPDRKKRYTVVGNPYWMAP PAK1 10559936
LTP
1.00
 - STYKc
0.29
 - medium

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